In vitroにおける歯科領域由来間葉系幹細胞のインシュリン産生細胞への分化の可能性

A feasibility study of an in vitro differentiation potential toward insulin-producing cells by dental tissue-derived mesenchymal stem cells Biochem Biophys Res Commun. 2014 Aug 30 [Epub ahead of print] Sawangmake C et al., Chulalongkorn Un…

臍帯由来間葉系幹細胞を歯の自家移植後の治癒に使用するための基礎研究

A fundamental study applying umbilical cord mesenchymal stem cells to the periodontium healing after tooth autotransplantation. Br J Oral Maxillofac Surg. 2014 Apr 30. [Epub ahead of print] Li Y et al., The Forth Military Medical Universit…

歯根膜および歯肉組織由来幹細胞の腱組織再生への応用

Application of stem cells derived from the periodontal ligament or gingival tissue sources for tendon tissue regeneration. Biomaterials. 2014 Jan 4. [Epub ahead of print] Moshaverinia A et al., University of University of Southern Californ…

Dentine sialoproteinは歯根膜幹細胞の増殖、分化を制御する

Domain of dentine sialoprotein mediates proliferation and differentiation of human periodontal ligament stem cells. PLoS One. 2013 Dec 3;8(12):e81655. Ozer et al., University of Texas Dentine sialoproteinは歯根膜幹細胞の増殖、分化を制御する…

歯根膜由来幹細胞はin vivoにおいて長期生存、自己増殖および複数組織への再生能力を示す

Periodontal Ligament Derived Stem Cells Exhibit the Capacity for Long-Term Survival, Self-Renewal and Regeneration of Multiple Tissue Types in Vivo. Stem Cells Dev. 2013 Dec 18. Menicanin D et al., University of Adelaide, Australia 歯根膜…

全身性に輸送された骨髄由来間葉系幹細胞の歯周組織再生における役割

The role of systemically delivered bone marrow-derived mesenchymal stem cells in the regeneration of periodontal tissues. Int J Oral Maxillofac Implants. 2013 Nov-Dec;28(6):e503-11. Yu et al., Beijing Institute of Trans fusion Medicine, Ch…

骨髄および歯根膜由来間葉系幹細胞の骨芽細胞分化は炎症条件下でCanonical Wntシグナリングによって異なる制御を受ける

Canonical Wnt signaling differently modulates osteogenic differentiation of mesenchymal stem cells derived from bone marrow and from periodontal ligament under inflammatory conditions. Biochim Biophys Acta. 2013 Nov 11. [Epub ahead of prin…

神経堤由来歯根膜幹細胞のEGFおよびbFGFによるニューロン形成

Neurogenesis of Neural Crest Derived Periodontal Ligament Stem Cells by EGF and bFGF J Cell Physiol. 2013 Sep 16. [Epub ahead of print] Fortino et al., University of Miami, USA 神経堤由来歯根膜幹細胞のEGFおよびbFGFによるニューロン形成 神経…

Connexin-43を用いた成体組織からの神経堤由来多能性幹細胞の単離

Isolation of pluripotent neural crest-derived stem cells from adult human tissues by connexin-43 enrichment. Stem Cells Dev. 2013 Nov 1;22(21):2906-14. Pelaez et al., Miami VA Healthcare System, USA Connexin-43を用いた成体組織からの神経堤…

TNF-alpha刺激に対するCD146陽性および陰性歯根膜細胞の反応の比較

Comparison of the properties of human CD146+ and CD146- periodontal ligament cells in response to stimulation with tumour necrosis factor alpha Arch Oral Biol. 2013 Dec;58(12):1791-803. Zhu et al., Sun Yat-sen University, China TNF-alpha刺…

歯根膜前駆細胞のin vivoにおける同定

In vivo Identification of periodontal progenitor cells J Dent Res 92(8):709-715, 2013 Roguljic et al., University of Connecticut Health Center, USA 歯根膜前駆細胞のin vivoにおける同定 歯根膜は歯周組織を形成する様々な細胞へ分化する能力を持…

歯根膜間葉系細胞の局所投与は軟組織再生を促進する

Local application of periodontal ligament stromal cells promotes soft tissue regeneration Oral Diseases (2013) doi:10.1111/odi.12175 Baik et al., Yonsei University, South Korea 歯根膜間葉系細胞の局所投与は軟組織再生を促進する 間葉系幹細胞…

低酸素はHIF-1依存的に歯由来幹細胞のセメント芽細胞分化を促進する

Hypoxia Promotes CEMP1 expression and Induces Cementoblastic Differentiation of Human Dental Stem Cells in a HIF-1 dependent Manner. Tissue Eng Part A. 2013 Oct 11. [Epub ahead of print] Choi et al., Seoul National University, South Korea …

歯根膜幹細胞は血管内皮細胞による機能的な血管新生を促進する

Stem Cells Derived from Tooth Periodontal Ligament Enhance Functional Angiogenesis by Endothelial Cells. Tissue Eng Part A. 2013 Oct 22. [Epub ahead of print] Yeasmin et al., Ann Arbor, United States 歯根膜幹細胞は血管内皮細胞による機能的…

同種異系由来の歯根膜幹細胞を用いた羊モデルにおける歯周組織再生

Regeneration of periodontal tissues using allogeneic periodontal ligament stem cells in an ovine model. Regen Med. 2013 Nov;8(6):711-23. doi: 10.2217/rme.13.66. Mrozik et al., University of Adelaide, Australia 同種異系由来の歯根膜幹細胞を…

歯根膜幹細胞の長期培養および幹細胞性維持のための最適な培養液について

Optimal Medium Formulation for the Long-Term Expansion and Stemness Maintenance of Periodontal Ligament Stem Cells J Periodontol. 2013 Oct;84(10):1434-44. Jung et al., Inha University, South Korea. 歯根膜幹細胞の長期培養および幹細胞性維持…