Downregulation of Wnt causes root resorption Am J Orthod Dentofacial Orthop. 2014 Sep;146(3):337-45. Lim et al., Seoul National University, Seoul, Korea. 背景：歯根の外部吸収については多くの原因があるが、病的状態が無い状態では矯正治療にお…
A Wnt-Responsive PDL Population Effectuates Extraction Socket Healing Journal of Dental Research 2018, Vol. 97(7) 803–809 Yuan et al., Stanford University, Stanford, USA 歯根膜(PDL)中に存在する幹細胞は歯周組織の恒常性維持に役割を果たしてい…
Are Hertwig’s epithelial root sheath cells necessary for periodontal formation by dental follicle cells? Archives of Oral Biology 94 (2018) 1–9 Guo et al., State Key Laboratory of Oral Diseases, Chengdu, China 目的：歯周組織形成におけるヘ…
Periodontal-Ligament-Derived Stem Cells Exhibit the Capacity for Long-Term Survival, Self-Renewal,and Regeneration of Multiple Tissue Types in Vivo Stem Cells Dev. 2014 May 1;23(9):1001-11. Menicanin et al., University of Adelaide, Adelaid…
Contribution of the PDL to Osteotomy Repair and Implant Osseointegration Journal of Dental Research 2017, Vol. 96(8) 909–916 Pei et al, Sichuan University, Chengdu, China 本研究の目的は抜歯後にソケット内に残存した歯根膜(PDL)のその後を明ら…
Cigarette smoking hinders human periodontal ligament-derived stem cell proliferation, migration and differentiation potentials Scientific Reports, 2015, 5 : 7828 Ng et al., The Chinese University of Hong Kong, Hong Kong, China 喫煙は破壊的…
Human Periodontal Ligament-Derived Stem Cells Promote Retinal Ganglion Cell Survival and AxonRegeneration After Optic Nerve Injury Stem Cells, 2018;36:844–855 Cen et al., Joint Shantou International Eye Center of Shantou University and The…
The promotion function of Berberine for osteogenic differentiation of human periodontal ligament stem cells via ERK-FOS pathway mediated by EGFR Scientific Reports (2018) 8:2848 Jin wt al., Xi’an Jiaotong University, China Coptidis Rhizoma…
A High-Resolution Proteomic Landscaping of Primary Human Dental Stem Cells: Identification of SHED- and PDLSC-Specific Biomarkers Int. J. Mol. Sci. 2018, 19, 158; Taraslia et al., Biomedical Research Foundation of the Academy of Athens, Gr…
Differentiation of hMSC and hPDLSC induced by PGE2 or BMP-7 in 3D models Prostaglandins, Leukotrienes and Essential Fatty Acids, 122(2017) 30-37 Ern et al., Ludwig-Maximilians-Universität München, Germany 歯周病学では病的な組織欠損に対する…
Human platelet lysate supports the formation of robust human periodontal ligament cell sheets J Tissue Eng Regen Med. 2018;12:961–972. Tian et al., Fourth Military Medical University, China 幹細胞を用いた細胞シートの利用が様々な医学的な用…
Osthole improves function of periodontitis periodontal ligament stem cells via epigenetic modification in cell sheets engineering Sci Rep. 2017 Jul 12;7(1):5254. Sun et al., Fourth Military Medical University, China 歯周炎組織から得られた…
Effect of cryopreservation on proliferation and differentiation of periodontal ligament stem cell sheets Stem Cell Research & Therapy (2017) 8:77 Li et al., Shandong University, China さまざまな生物材料の長期保存に凍結保存法が広く使われて…
Lipopolysaccharide can modify differentiation and immunomodulatory potential of periodontal ligament stem cells via ERK1,2 signaling J Cell Physiol. 2018;233:447–462. Tamara et al., University of Belgrade, Serbia リポ多糖(LPS)は口腔環境に…
Periodontal ligament stem/progenitor cells with protein-releasing scaffolds for cementum formation and integration on dentin surface. Connect Tissue Res. 2016 Nov;57(6):488-495. Epub 2016 May 23. Cho et al., Columbia University Medical Cen…
Cementogenic genes in human periodontal ligament stem cells are downregulated in response to osteogenic stimulation while upregulated by vitamin C treatment Cell Tissue Res (2017) 368:79–92 Gauthier et al., Boston University, Boston, USA. …
Investigation of the Cell Surface Proteome of Human Periodontal Ligament Stem Cells Stem Cells International, Volume 2016, Article ID 1947157, 13 pages Xiong et al., University of Adelaide, Adelaide, Australia 本研究では、ヒト歯根膜幹細胞…
Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging Li Q.et al., J Periodontol 2017: 88(1), e12-23. Peking University School and Hospital of Stomatology 老化にかかわる幹細胞（SC)機能の低下を制御…
The use of platelet-rich fibrin combined with periodontal ligament and jaw bone mesenchymal stem cell sheets for periodontal tissue engineering Scientific Reports 2016 Jun 21;6:28126. Fourth Military Medical University, China. 歯周組織再生…
Assessment of cellular materials generated by co-cultured ‘inflamed’ and healthy periodontal ligament stem cells from patient-matched groups Experimental Cell Research 346 (2016) 119–129 Tang et al., Fourth Military Medical University, Chi…
Bio-Root and Implant-Based Restoration as a Tooth Replacement Alternative Journal of Dental Research 2016, Vol. 95(6) 642–649. Gao et al., Capital Medical University School of Stomatology, China 我々は過去に歯科領域の幹細胞を用いた組織工学…
Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial Chen et al., Stem Cell Research & Therapy (2016) 7:33 Fourth Military Medical University, China 歯の支持組織を進行性に…
Adenovirus-mediated transfer of hepatocyte growth factor gene to human dental pulp stem cells under good manufacturing practice improves their potential for periodontal regeneration in swine Cao et al., Stem Cell Research & Therapy (2015) …
Tissue-specific composite cell aggregates drive periodontium tissue regeneration by reconstructing a regenerative microenvironment J Tissue Eng Regen Med. 2017 Jun;11(6):1792-1805. Zhu B et al., Fourth Military Medical University, China 歯…
Effects of In Vitro Osteogenic Induction on In Vivo Tissue Regeneration by Dental Pulp and Periodontal Ligament Stem Cells. J Endod. 2015 Sep;41(9):1462-8. Cha Y et al., Yonsei University, Korea. 本研究の目的は、in vitroでの骨芽細胞/セメン…
Age-related decline in the matrix contents and functional properties of human periodontal ligament stem cell sheets Acta Biomater. 2015 Aug;22:70-82. Wu RX et al., Fourth Military Medical University, PR China 本研究では、異なる年齢の患者か…
Synergistic Effects of a Calcium Phosphate/Fibronectin Coating on the Adhesion of Periodontal Ligament Stem Cells Onto Decellularized Dental Root Surfaces Lee JS et al., Yonsei University, Seoul, Republic of Korea Cell Transplant. 2015;24(…
Mesenchymal stem cell characteristics of dental pulp and periodontal ligament stem cells after in vivo transplantation. Biomaterials. 2014 Aug;35(24):6332-43. Lei M et al., Fourth Military Medical University, China 出生後の歯髄あるいは歯根…
Scaffold-Free Cell Pellet Transplantations can be Applied to Periodontal Regeneration Cell Transplantation, Vol. 23, pp. 181–194, 2014 Fourth Military Medical University, China 細胞移植が歯周病の新規治療法として提唱されているが、細胞ペレッ…
Preclinical Assessment of the Proliferation Capacity of Gingival and Periodontal Ligament Stem Cells from Diabetic Patients Open Access Maced J Med Sci. 2018 Feb 1;6(2):254-259. doi: 10.3889/oamjms.2018.076. eCollection 2018 Feb 15. Mostaf…
